Sunday, March 22, 2020

The Jungle Essays (782 words) - Meat Packing Industry, The Jungle

The Jungle Upton Sinclair's The Jungle is the story of a Lithuanian family that immigrates from their home city in Lithuania to the city of Chicago. The novel begins with the strong description of a wedding in which Ona Lukoszaite and Jurgis Rudkus are united in Holy Matrimony. The two of them then move to Chicago. Soon after the wedding, Ona and Jurgis have many great debts to pay due to both the wedding and a large debt that Ona's father left them after he died. Due to Jurgis' large size and strong will he found a job in Chicago within only a half an hour of waiting in the unemployment line. Back in the newlywed's hometown of Lithuania, Ona and Jurgis' family anticipated a move to America. America uses the image of the ?American Dream? to lure immigrants to this land of opportunity. The family desperately desires higher wages and true freedom. For months and months, Jurgis works very hard to pay for the families travel to Ona and Jurgis' new hometown, Chicago. When the family finally makes it to America, their funds are very low. They met with a well off man named Jokubas Szedvilas who placed the family in a run down youth hostel. Jokubas takes the family to the meatpacking factory. He makes jokes about the sanitation of the operation (due only to the lack of quality of the meat). The family finds an advertisement for a housing complex that is very cheap. They talk to a real estate agent and they go see the housing complex. The houses aren't as big and luxurious as they are pictured in the advertisement, but the price is right. The real estate agent swindles them, and they are pulled into the contract. Sinclair emphasizes the corruption of upper class society during this era. Jurgis' father, Dede Antanas, is promised a job by a grubby worker, but only if he pays that worker one third of his wages. He takes the job despite the disgusting working conditions and his low pay. Jurgis is a very hard worker. He is the only person in the meat plant that doesn't complain. He doesn't think much of the other workers. He feels that they never get any work done, and all they do is gripe. Marija, Ona's cousin and Jonas, Ona's step brother, both get jobs, but neither one holds them for very long. From there things take a turn for the worst. The meat packing factories prove to be very unsanitary. Animal fetuses and even human corpses were processed, packaged, and distributed to the country. Working conditions became even worse for Jurgis, and after both his wife and child die, he left his job and family. Jurgis, now struggling more and more for money, turns to crime. The slums of Chicago show great contrast between the upper class and the underprivileged. The majority of the immigrant society possess very little money. Jurgis, an underprivileged person, must make his money illegally. He wanders the city aimlessly taking continuous criticism from the upper class of Chicago. He returned home to find that Ona's stepmother's child, Stanislovas, who once had a great fear of the cold after a frostbite incident, has tragically been eaten alive by a pack of rats on the job. He also finds out that his cousin in law Marija has become a whore to make money for herself. Jurgis tries to convince her to give it up, but she become addicted to morphine and she depends on the money. Jurgis' life has hit a dead end. He only finds light when he hears a political speaker involved with the Socialist party. He feels that an oversized proportion of a government is the only thing to uplift people of his kind. Back then, in the United States, being poor was a terrible crime in its self. I believe that these people looked toward a more Socialistic government because this type of government would take some of the power from the upper class and would give it to the poor. These people were working terrible shifts in horrible working conditions. If they were born poor they would remain that way unless they really got lucky, the same as

Thursday, March 5, 2020

Exceptions in the Rules of Hyphenation

Exceptions in the Rules of Hyphenation Exceptions in the Rules of Hyphenation Exceptions in the Rules of Hyphenation By Mark Nichol After thumbing through the dictionary or perusing a usage guide, you’d think that the trend in American English and, to a lesser extent, in British English is to omit hyphens from words consisting of a prefix attached to the root word. But reality begs to differ. Mail sent from nonprofit organizations invariably features the word non-profit in the upper right-hand corner, where a stamp would normally be placed. (By contrast, the US Postal Service, on its Web site, correctly styles the term nonprofit but the Internal Revenue Service employs the hyphen, as do many such organizations.) Commercial Web sites and product catalogs invite customers to plan ahead, using the word pre-order, though the dictionary listing is preorder. And many print or online references to peace movements feature the term anti-war, despite the designation of the standard form in virtually all writing resources as antiwar. So, why do descriptivist and prescriptivist handbooks alike exhort readers to close the gap, when so many people who use the English language to communicate in writing ignore or are ignorant of the authorities’ citations? The natural trend in associating words or parts of words is to first combine them in open compounds, later hyphenate them as they become more established, and finally convert them into closed compounds when familiarity is thoroughly achieved (though many compounds remain open or hyphenated long after these evolutionary stages seem overdue). But most writers seemingly a majority of amateurs and definitely too many professionals don’t pay attention to such details, though the standard is easily ascertained by a glance in a dictionary or another resource. The exceptions to the preponderance of closed prefixes are relatively few and more or less simple. Retain a hyphen in the following cases: When the root word is a proper noun (post-Depression) or a number (pre-1914) When the prefix precedes an existing prefix (non-self-governing) When the prefix precedes a proper open compound (â€Å"pre-Civil War†) in such a case, the symbol should technically be an en dash, to help clarify that pre- modifies â€Å"Civil War,† not just the word it is actually attached to, but many publications, print and online, use a simple hyphen When two instances of the letter i or the letter a are adjacent (anti-intellectual, extra-action), or another combination of letters could hamper reading (pro-labor and many other pro- constructions) When a prefix is repeated (anti-antibody) When suspensive hyphenation is employed (â€Å"over- and understimulation†) Also, some people find it awkward to close up co- and a word starting with c (they prefer co-chair to cochair), with o (co-owner is preferred to coowner), or even with any word (coworker, instead of co-worker, annoys many writers). In addition, there are isolated illogical exceptions. For example, why close up reentry but hyphenate de-emphasis? And an otherwise superfluous hyphen is often inserted to distinguish homographs (as with re-count, â€Å"to tally again,† as opposed to recount, â€Å"to narrate†). Some writers ignore this seemingly overcautious strategy, though a clear context doesn’t necessarily obviate it. (Sometimes, the distinction does seem unnecessary: How many people write recreate as the verb form of recreation compared to using the prevalent usage, meaning â€Å"to create again†? But, oddly, the dominant homograph is given the hyphenated form.) Despite this apparent multitude of deviations from the norm, there is a norm: An overwhelming majority of prefixes are closed. But if you’re ever in doubt, just consult your dictionary. Want to improve your English in five minutes a day? Get a subscription and start receiving our writing tips and exercises daily! Keep learning! Browse the Grammar category, check our popular posts, or choose a related post below:Spelling Test 15 Brainstorming Strategies for Writers20 Names of Body Parts and Elements and Their Figurative Meanings

Tuesday, February 18, 2020

The importance of analysis and analitical skills to the manager making Essay

The importance of analysis and analitical skills to the manager making decisions in business - Essay Example Business opportunity of get fit quick Competition, coupled with increased changes in the business environment, has combined to execute powerful impact on the way managers and their different organizations conduct businesses. In this regard, organizations have been forced to develop and implement the most sophisticated decision-making techniques in order to ensure available resources are economically and optimally utilized. In order for business to get fit quickly and successfully, managers are required to explore the different available alternatives of decision-making. The alternatives should have the ability to outline, in the most efficient way, how the organization can make use of the available resources in a way that differs from competitors and give returns that enable the business to create competitive advantage (Casey and Capella University 2006). Available resources in an organization can be used in ways that provide opportunity for the organization to achieve maximum utility. However, this is possible through selecting the best alternatives of decision-making as it pertains to resource utilization, environmental scanning, and goals to be achieved. Approaches of decision-making process Management literature depicts that decision-making process can benefit greatly from the four main approaches that are generally used in making decisions. As a result, in order for decision-making process to be successful and productive, managers are either to select one or multiple approaches that include logical systems approach, contingency approach, quantitative approach, and the qualitative approach. Logical systems of decision-making are premised on the rationality essence that is needed to make decisions (Wysocki 2010). In this case, an individual (manager) is perceived to have rational set of stages that should be followed before arriving at the appropriate conclusion regarding decision (Wysocki, 2010). Contingency approach on the other hand categorizes or program alternatives that can be used to achieve decision goals (Sengupta and Bhattacharya, 2006). A problem is presented to have different ways of solving it and this lead to development and evaluation of different ways of finding solution. On the other hand, quantitative approaches dictate that, decision-making process succeed when concept such as project management are adopted (Anderson, 2011). In this way, figures are seen to possess great ability of providing management with chances of finding solut

Monday, February 3, 2020

The impact of environmental laws on property management in the UK Dissertation

The impact of environmental laws on property management in the UK - Dissertation Example Projections are given in regards to the overall success in a broad sense of the present model of progress benchmarks along the way towards safer industry and human activity with respect to Earth's ecosystems. These needs are compared with the goals and interests of property owners. Table of Contents Declaration †¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.. p.4 Preface †¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.. p.4 Introduction †¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.. p.4 Literature Review Part One †¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.. p.5 Literature Review Part Two †¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.. p.35 Literature Review Part Three †¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.. p.45 Methodology †¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.. p.59 Findings †¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.. p.59 Conclusion and Recommendations †¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.. p.61 References †¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.. p.65 Declaration As a part of the European Union, the United Kingdom must adapt existing territor ial legislation into harmony with existing environmental policy. Most modern environmental legislation in Europe is passed down from United Nations International treaties, to be ratified by the European Union, and disseminated for review to individual nation states. All property owners have an obligation to respond to environmental policies and regulations, even those not engaged in heavy industrial waste production. Preface This study constitutes an analysis of environmental regulations as they exist in the United Kingdom pertaining to housing and property management. The practice of environmental regulation and enforcement is detailed. Findings, conclusions and recommendations follow the primary literature review. Introduction The most basic definition of the environment would be that which is not ourselves, and yet we all live in a world of interconnectedness and interrelationships were all are affected by the actions of others whether or not we are aware of them. A more detailed legal definition is in order, however: "Environment shall mean the space with all living organisms and natural resources, natural and man-made values, their interaction and the entire space in which people live and in which settlements, goods in general use, industrial and other facilities, including the media in the areas of the environment, are situated. " (Home, 2007) It is reasonable suppose that any contrived separation of any individual or organization from the environment is an illusion. And it is thus the responsibility of all citizens, and all commercial enterprises to cultivate a principle of stewardship for and within their greater environment. This study will relate principally to environmental policies pertaining to property ownership in the United Kingdom, specifically the rules and regulations in regards to legal compliance with environmental laws relevant to both residential and commercial property owners. The intent of environmental policy will be described in acco rdance with United Nations and European Union mandates which are then disseminated into laws by the various member nations. The means by which these laws are implemented, the challenges in their implementation, and the ramifications of these legal principles for the environment and for the rights of property owners shall be detailed. Literature Review Part One There is no doubt as to the necessity of a certain responsible level of environmental regulation in the field of housing and property management. The importance of environmental controls can be regularly seen in clean air and pristine water, especially when it is contrasted

Sunday, January 26, 2020

Methods for Water Treatment

Methods for Water Treatment 1.12.2 Effect of chlorination of water Chlorine is toxic not only for microorganisms, but for human being also. For humans, chlorine is an irritation to the nasal passages eye, and respiratory system. Chlorine gas must be cautiously handled because it may cause severe health problem. Although, chlorine gas is also the low rate form of chlorine for water treatment, It makes use choice in spite of the health problem. In drinking water, the concentration of chlorine is usually very low and is thus not a concern in acute exposure. More of a concern is the long term risk of cancer due to chronic exposing to chlorinated water. This is mainly due to the halo alkanes and other products and chlorinated products. These are carcinogenic and have been the substance of concern in chlorinated drinking water. Chlorinated water has been related with increased risk of bladder, colon and rectal cancer. In the case of bladder cancer, the risk may be doubled. Chlorination is a very popular method of water disinfection that has been used from several years. It has proved to be efficient for destroying bacteria and viruses, but not for some carcinogenic disinfection by-product, many communities have become hesitant in the continuation of this process. Although chlorination does have some disadvantages, it continues to be the most conventional, useful, and consistent method of water disinfection. 1.13 Oxidation by potassium permanganate Most treatment plants, uses potassium permanganate for the oxidation and subsequent removal of iron, follow the chemical addition with manganese greensand filtration. Manganese treated greensand can exchange electrons and therefore oxidizes iron and manganese to their insoluble, filterable states [[1][2]]. When the filter is completely regenerated the excess KMnO4 will break through the filter bed leaving a pink color in the water. The greensand filter bed is usually capped with anthracite to first remove insoluble compounds, which helps prevent the filter from becoming clogged. Most filters are equipped with an air wash system to enhance the greens and backwashing process. Major disadvantages to the use of the potassium permanganate – greens and filtration process for iron removal include high chemical costs and filter bed deterioration when the pH falls below 7.0. In some treatment plants, KMnO4 is used to oxidize iron and manganese without greensand filtration[[3]]and analytical chemistry [[4]] and also as a disinfectant. Among the six oxidation states of manganese from +2 to +7, permanganate, Mn(VII) is the most pervasive oxidation state in acid, with reduction potentials of [[5]]Oxidation by permanganate finds extensive application in organic synthesis [[6]].The manganese c hemistry involved in these multistep redox reactions is an important source of information as the manganese intermediates are relatively easy to identify when they have sufficiently long lifetimes, and oxidation states of the intermediates permit useful conclusions as to the possible reaction mechanisms, including the nature of intermediates. In acidic medium it exists in the different forms: HMnO4, H2MnO+4, HMnO3 and Mn2O7. The thesis comprises seven chapters including the general introduction about chemical kinetics as follows. 1.  General Introduction This chapter introduces about the kinetics, mechanisms, disinfection and catalysis of reactions in general. PART I Uncatalyzed reactions 2. Transformation of Levofloxacin during Water treatment with chlorine: Kinetics, Mechanism and Pathways Kinetics and mechanism of removal of fluoroquinolone antibacterial levofloxacin (LFC) by free available chlorine (FAC) during water chlorination processes was investigated for the first time between the pH values 4.2 and 8.5. The pH dependent second order rate constants were found to decrease with increase in pH. (e.g. Apparent second order rate constant; k†app = 20 dm3 mol-1 s-1 at pH 4.2 and k†app = 1 dm3 mol-1 s-1 at pH 8.5 and at 25 oC). The products of the reaction were determined by Liquid chromatography and high resolution mass spectrometry. There are two plausible pathways for the LFC chlorination. The major channel is electrophilic halodecarboxylation of quinolone moiety in which, HOCl reacts at tertiary N(4) amine to form a reactive chlorammonium intermediate (R3N(4)Cl+) that can catalytically halogenate LFC and the minor channel is chlorination at piperazinyl moiety in which the HOCl reacts at tertiary N(4) amine to form a reactive chlorammonium intermediate (R 3N(4)Cl+) followed by intermediate degradation both at piperazinyl and quinolone moiety with successive chlorination. The effect of temperature on the rate of the reaction was studied at four different temperatures and rate constants were found to increase with increase in temperature and the thermodynamic activation parameters Ea, ΔH#, ΔS# and ΔG# were evaluated for the reaction and discussed. 3. Transformation of linezolid during water treatment with chlorine: A kinetic study The experimental studies on transformation of emerging contaminant linezolid during water chlorination process have been carried out using UV-Visible spectrometer. The pseudo-first order rate constants of linezolid reaction with free available chlorine (FAC) at 5.0 to 8.8 pH have been determined. The second order rate constants are found to decrease with increase in pH (e.g. apparent second rate constant; k†app=2.88 dm3 mol-1s-1 at pH 5.0 and k†app = 0.076 dm3 mol-1 s-1 at pH 8.8 at 298K). Monochlorinated reaction product has been identified by LC/ESI/MS spectra under the experimental conditions. A mechanism involving electrophilic halogenation is proposed based on the kinetic data and LC/ESI/MS spectra. The effect of temperature on the rate of the reaction has been studied at four different temperatures. It is observed that rate constants increase with the increase in temperature and the thermodynamic activation parameters Ea, ΔH#, ΔS# and ΔG# are evaluated for the reaction and discussed. The product of the reaction between linezolid and FAC retains the antibacterial activity. The geometry optimization of the reactants and the products has been done using dispersion corrected density functional (DFT-D) method. All the DFT calculations are accomplished using the TurboMole-5.10 package. 4. Transformation of antibacterial agent lomefloxacin by alkaline permanganate: Kinetics and Mechanism The kinetic and mechanistic investigation of oxidation of emerging contaminant Lomefloxacin (LMF) by alkaline permanganate was carried out spectrophtometrically. The oxidation product 7-amino-1-ethyl-6,8-difluoro-4-oxo-quinoline-3-carboxylic acid was identified by Agilent 6130 Series Quadrupole LC/MS. The stoichiometry was found to be 1:2, that is, 1 mol of lomefloxacin reacted with 2 mol manganese (VII). Orders with respect to [LMF] and [OH] were found to be fractional and less that one. The oxidation reaction proceeds via an alkali-permanganate species, that forms a complex with lomefloxacin and the complex then decomposes to give the product. The rate of reaction was found to decrease with decrease in the dielectric constant. The effects of initially added products and ionic strength have also been investigated. The kinetics of the reaction was also studied at four different temperatures and the thermodynamic activation parameters for the reaction were evaluated and discussed. The geometry optimization of reactants and activated complex were carried out using density functional theory (DFT). The DFT calculations were accomplished with the TURBOMOLE program package (Version-6.4). The activation energy was found to be ~21 kJ/mol at RI-BP86.def 2-TZVPP level of theory. PART II CATALYSED REACTIONS 5. Silver (I) catalyzed and uncatalyzed oxidation of levofloxacin with aqueous chlorine: A comparative kinetic and mechanistic approach The kinetics and mechanism of the Ag (I) ion catalyzed reaction of levofloxacin (LFC) by free available chlorine (FAC) during water chlorination processes was investigated for the first time between the pH values 4.2 and 8.2. The pH dependent second order rate constants were found to decrease with increase in pH. (e.g. Apparent second order rate constant for Ag (I) catalyzed reaction, k†app = 114.40 dm-3 mol-1 sec-1 at pH 4.2 and k† app. = 8.72 dm-3mol-1 sec-1 at pH 8.2 and at 25 ±0.2 à ¢Ã¢â‚¬Å¾Ã†â€™). The reaction rates revealed that Ag (I) catalyzed reaction was about six-fold faster than the uncatalyzed reaction. The products of the reaction were determined by Liquid chromatography and high resolution mass spectrometry. The reaction proceeds via formation of intermediate complex between Ag (I) ion and levofloxacin, then HOCl reacts with the complex to form chlorinated product. The effect of catalyst, effect of initially added product, effect dielectric constant and effect ionic strength on the rate of reaction was also studied. The effect of temperature on the rate of the reaction was studied at four different temperatures and rate constants were found to increase with increase in temperature and the thermodynamic activation parameters Ea, ΔH#, ΔS# and ΔG# were evaluated for the reaction and discussed. 6. Ag (I) catalyzed chlorination of linezolid during water treatment: Kinetics, mechanism The kinetics and mechanism of the Ag (I) ion catalyzed reaction of linezolid (LNZ) by free available chlorine (FAC) during water chlorination processes was investigated for the first time between the pH values 4.0 and 9.0. The pseudo-first order rate constants of linezolid reaction with free available chlorine (FAC) at 4.0 to 9.0 pH have been determined. The pH dependent second order rate constants were found to decrease with increase in pH. Apparent second order rate constant for uncatalyzed reaction, e.g. k†app = 8.15 dm-3 mol-1 sec-1 at pH 4.0 and k† app. = 0.076 dm-3mol-1 sec-1 at pH 9.0 and at 25 ±0.2 à ¢Ã¢â‚¬Å¾Ã†â€™ and for Ag (I) catalyzed reaction total apparent second order rate constant, e.g. k†app = 51.50 dm-3 mol-1 sec-1 at pH 4.0 and k† app. = 1.03 dm-3mol-1 sec-1 at pH 9.0 and at 25 ±0.2 à ¢Ã¢â‚¬Å¾Ã†â€™. The reaction rates revealed that Ag (I) catalyzed reaction was about five to ten-fold faster than the uncatalyzed reaction. Monochlorinate d reaction product has been identified by LC/ESI/MS spectra under the experimental conditions. A mechanism involving electrophilic halogenation is proposed based on the kinetic data and LC/ESI/MS spectra. The reaction rates revealed that Ag (I) catalyzed reaction was about ten-fold faster than the uncatalyzed reaction.The reaction proceeds via formation of intermediate complex between Ag (I) ion and linezolid, then HOCl reacts with the complex to form chlorinated product. The effect of temperature on the rate of the reaction has been studied at four different temperatures. It is observed that rate constants increase with the increase in temperature and the thermodynamic activation parameters Ea, ΔH#, ΔS# and ΔG# are evaluated for the reaction and discussed. The effect of catalyst, effect of initially added product, effect dielectric constant and effect ionic strength on the rate of reaction. The product of the reaction between linezolid and FAC retains the antibacterial activity. 7. Transformation of linezolid during water treatment with permanganate: Kinetics, mechanism and Pd (II) catalysis The uncatalyzed and Pd (II) catalyzed transformation of Linezolid (LNZ) with permanganate in acidic medium was carried out between the pH values 3.0 and 6.0. The pH dependent second order rate constants were found to decrease with increase in pH. Apparent second order rate constant for uncatalyzed reaction, e.g. k†app = 6.32 dm-3 mol-1 sec-1 at pH 3.0 and k† app. = 2.64 dm-3mol-1 sec-1 at pH 6.0 and at 25 ±0.2 à ¢Ã¢â‚¬Å¾Ã†â€™ and for Pd (II) catalyzed reaction total apparent second order rate constant, e.g. k†app = 75.5 dm-3 mol-1 sec-1 at pH 3.0 and k† app. = 45.66 dm-3mol-1 sec-1 at pH 6.0 and at 25 ±0.2 à ¢Ã¢â‚¬Å¾Ã†â€™. The reaction rates revealed that Pd (II) catalyzed reaction was about ten-fold faster than the uncatalyzed reaction. The products of the reaction were determined by Liquid chromatography and high resolution mass spectrometry. The reaction proceeds via formation of complex between Pd (II) and linezolid, then complex reacts with acidic p ermanganate to form intermediate compound, which then form oxidized products. The effect of catalyst, effect of initially added product, effect dielectric constant and effect ionic strength on the rate of reaction were also studied. The effect of temperature on the rate of the reaction was studied at four different temperatures and rate constants were found to increase with increase in temperature and the thermodynamic activation parameters Ea, ΔH#, ΔS# and ΔG# were evaluated for the reaction and discussed. References [1]. w. Stumm, and J.J. Morgan, Aquatic Chemistry. Wiley Interscience, New York, 1967. [2]. J. Hoigne, H. Bader, W.R. Haag and J. Staehelin, Rate Constants of Reactions of Ozone with Organic and Inorganic Compounds in water III, Water Res., Vol. 19(8), 1985, pp.993. [3]. L.D. Benefield, J.F. Judkins and B.L. Weand , Iron and Manganese Removal, from Process Chemistry for water and wastewater Treatment, ed. J.M. Chege, Prentice Hall, Inc., Englewood CliffS, N.J.,1982. [4]. G.A. Hiremath, P.L.Timmanagoudar and S. T. Nandibewoor, Kinetics of oxidation of thallium (I) by permanganate in aqueous hydrochloric acid medium using stopped flow technique. Transit. Met. Chem. Vol.21, 1996, pp. 560–568. [5]. M.C. Day and J.Selbin, Theoretical Inorganic Chemistry, Reinhold, New York, 1964,  pp. 226–233. [6]. P. Caron, R.W. Dugger, J.A.Ruggeri and D.H.Brown Ripin, Large scale oxidations in the pharmaceutical industry. Chem. Rev. Vol.106, 2006, pp. 2943–2989.

Saturday, January 18, 2020

Emergency Department Poc Immunoassay Testing Essay

Introduction Cardiovascular disease is a substantial concern and has emerged as one of the leading health issues. In examining cardiovascular disease, its incidence is astounding. Each year approximately one million men and women die, averaging one death every thirty three seconds (Heart, 2013).The death rate for cardiovascular issues such as myocardial infarction and CHF claim more lives than cancer and Aids combined. Heart disease will be the number one cause of death by the year 2020 worldwide (Heart, 2013). Notably heart disease is a significant health problem that not only costs lives but is a significant economic burden with costs related to doctors’ visits, medications, rehabilitation and additional contributors such as loss of work and patient rehabilitations. It is estimated at approximately 485 billion dollars annually can be associated to the treatment of heart related issues such as heart attack and CHF, early diagnosis is imperative (Heart,2013). The intention of this proposal is to introduce the function of Point of care (POC) testing in the Emergency Department for immunoassay levels and educate on the benefits of early detection of Troponin and Brain naturietic peptide levels which are cardiovascular disease markers. This proposal outlines the purpose, targeted population, costs, and benefits as well as the process of evaluation. Furthermore, acquiring approval of the Emergency Department manager as well as the director is the intention of this proposal and it is hoped that the program once approved can be launched in June of 2015. Purpose of the Program The purpose of the program is to promote is to acquire funding for the purchase of an immunoassay point of care testing machine in the Emergency Department(ED). Heart disease effects millions of people worldwide, often patients present to the Emergency Department in need of testing for heart related issues. Often times the chest pain and symptoms people are experiencing are benign, in utilizing the POC testing patients  people can be quickly assessed for cardiac markers and if negative will result unnecessary precautionary medication utilization, decrease in unnecessary overnight observation, shortened length of stay in the ED as well as reduction in patient anxiety waiting for lengthy lab results (Noyan, 2013). Target Population The target population includes men and women greater than age 18. Although heart related issues such as cardiovascular disease and CHF most commonly affect persons greater than 65 and estimated 1% of the population can be stricken with disease as early as age 18. Often times drugs may be a factor as well as genetics (Heart, 2013). It is imperative all persons presenting to the ER with chest pain or other heart related issues be cleared for any possible life threating cardiac events. There are an estimated 250,000 sudden cardiac deaths occurring each year in the united states, that translates into 680 per day, half of this is in persons younger than 65 and in addition half of these have no prior warning symptoms (Heart,2013). Looking at these statistics it is imperative that having POC testing to rule out benign conditions and reserve resources for true life threating cardiac issues. Costs Once the purchase of the device is made its annual costs are slim. With the cost of health care rising and less insurance reimbursement saving money for the hospital is vital. The purchase price for the POC device is approximately 6,000 dollars which based on a study translated into approximately 9.00 to per person to perform the test which is very inexpensive( Mainor,2002). Benefits Benefits of this program is receiving funding for the purchase of the POC testing equipment, resulting in the ability to rapidly evaluate patients presenting with cardiovascular symptoms, such as suspected acute myocardial infarction or heart failure. Utilizing POC testing into an emergency department results in quicker diagnosis, treatment, improved patient outcomes, improves ER flow through by weeding out non acute patients, decreases unnecessary use of resources such as medication and  hospital admissions. Evaluation In order to assess if this program will be successful we can survey a control group to see if the statements that are made are accurate. In surveying 100 patients that present with cardiovascular symptoms such as chest pain. POC testing can be completed to see how many of the 100 patients were non acute chest pain resulting in the reduction of resources and admissions. In addition, research from other facilities is widely available and research has already been completed ensure the success of this program. Conclusion POC testing is an easy, quick intervention that leads to quicker diagnosis and the savings of vital resources need for life threatening emergencies. This department needs to have this machine, the improvement of ER flow by reducing non acute patient wait times would be only one of many invaluable reasons to approve and fund this program. References: Heart Disease and Stroke Statistics–2013. (2013). Journal of the American Heart Association, 127(6), 1-245. Mainor, B., Hardwick, W., & King, W. (January,2002). Evaluation of a Portable Clinical Analyzer in the Pediatric Emergency Department: Analysis of Cost and Turnaround Time. Southern Medical Journal, 95(6), 4-5. Retrieved October 6, 2014. Noyan, T., Gozlukaya, O., & Cankaya, S. (2013). The Evaluation of Cardiac TroponinI Assays Measured Radiometer AQT90 Flex and ReLIA Analyzers. Journal of Medicine and Medical Research, 1(4), 16-22.

Friday, January 10, 2020

A Contemporary Take on The Blithedale Romance

Four individuals get together with thoughts on what an ideal society should be in Nathaniel Hawthorne’s â€Å"The Blithedale Romance. † Blithedale was a modern Arcadia founded by Charles Fourier which was eventually destroyed by the behavior of individuals who are only interested for themselves. These said members are the very four individuals who are the main characters in the novel.These are Hollingsworth, a philanthropist and misogynist who wants to make Blithedale a colony for the reformation of criminals, Zenobia, an outspoken and opinionated feminist, Priscilla, a seamstress from the city and Miles Coverdale, the poet who is also the narrator in the story. Throughout spring and summer, Hollingsworth, Zenobia, Priscilla and Coverdale formed an intense friendship with one another. Just like the weather, this bond disintegrates the exact moment autumn comes. The book ends tragically. Coverdale is an unreliable narrator.It was as if his manner of speaking represents s pirituality to the masses who are already secular. This makes him appear someone who tries to popularize his beliefs. He is also a voyeur because he avoids interaction with those around him. He also doesn’t like to be seen. Since he is the narrator, it seems as if he has the power. Truth is, his personality influences how the story is told. The politics, personal liberation and communal utopia he has in his head still depends on how the three other characters take it. Zenobia is the representation of the eternal feminine, to the delight of modern-day feminists.The text describes her as â€Å"earthy, maternal, natural, sensual, domestic, brilliant, loving and demanding. † Nonetheless, Zenobia is complicated and she represents the varying feminist qualities just as she mirrors the â€Å"materiality of the world† and her â€Å"resistance to desire. † It seems as if Zenobia was already the image of the feminist politics. On the other hand, Hollingsworth is of ten perceived as the American sterotype. He intends to â€Å"convert the heathen. † This is his way to redeem the fallen. He has projects that are philanthropic by nature. It masks his â€Å"will to power.† Hollingsworth is the typical white and male of today. It also seems that throughout the text, he is so masculine. Each trait he has reflects traditional masculinity. Finally, there is Priscilla. She is the exact opposite of Zenobia. She is passive, innocent, vulnerable and can easily be manipulated. She suffers from the control of the men in her life. However, in the book as written by Hawthorne, it will seem that Priscilla overpowers Zenobia. In the society that they are in, Zenobia’s strong feminist views do not coincide with the traditional norms.†The Blithedale Romance† may be a classic but it is still relevant especially during political seasons. With the background check on the time Hawthorne wrote this, the Transcendentalists, Utopian Movem ent, Unitarians and Universalists still remain in the political ideologies of today. Just like modern Americans, the characters in the story are unsatisfied with what the United States is now. They believe that they are still living in the â€Å"sinfulness of man. † They intend to make heaven here on earth. In the book, they called their utopia â€Å"Happy Valley.† We see politicians striving for the same goal today. Each one of them have their own logos. In contemporary America, politicians always trying to fix things that do not need fixing. They believe they can ignore human nature.. It is interesting to point that the ideologies represented in the book didn’t work. It is pretty much a prediction because these movements – Socialism, Misogyny, Feminism – also do not work today. The part where Zenobia seems to be uncontrolled is an allusion to the power of the feminist movement. If you think about it, women want to be heard.They have strong convic tions and if the reader will use Zenobia as the symbol of the feminist movement, he can conclude that she bowed down to Hollingsworth, who represents the traditional male. It is unfortunate that despite women’s determination to be heard, the masculine driven society we live in today results to an â€Å"abrupt and dramatic suicide† of the feminist’s beliefs. 1 Hawthorne, during his time, was known to be a romance novelist. This work is different from his previous masterpieces simply because of its relative realism.He made sure that the novel deals with social events that occur in an everyday fashion. There is also romance in extraordinary events. The novel manages to analyze the characters through the historical and social forces. Take this for example. A main complication in the novel is the conflict between the individual and the community. There is a subjectivity on the self because the focus is on will and personal freedom. Early on, it has been said that the town did not succeed because of the self-interest of the four characters.That is why as much as the characters offer ethical benefit in order for the other person to do well, the individualism appears to be self detemination. The pursuit of one’s personal gain only complicates the matter even more. 2 Another conflict is Hollingsworth’s take on spirituality. It seems that it is so intangible that it needs public reckoning but most individuals in Blithedale wish to see this spiritual belief in evidence which the four characters cannot explain. Clearly, â€Å"The Blithedale Romance† is a romantic perception of something so real such as a society.As much as one wishes to strive for utopia, the human nature of selfishness, self-interest and self-again will always prevent this from happening. Another concern is the different mindsets of people, as seen among the four characters in â€Å"The Blithedale Romance. † This only comes to show that there will always b e misunderstanding among us. 1 Hoeltje, Hubert H. Inward Sky: The Heart and Mind of Nathaniel Hawthorne, page 313, Duke University Press, 1962 2 Craig White, â€Å"A Utopia of Spheres and Sympathies†, Utopian Studies, 1998.